This course provides students with theoretical understanding and practical, embodied knowledge of how the arts and aesthetics can be a resource for fostering existential resilience. Existential resilience is about our intrinsic ability, and need, to create and experience meaningfulness, beauty, and to develop connection with and compassion for ourselves, others and the world, also in conditions of crisis, loss and difficulty. Those human abilities lie at the core of the arts and aesthetics, which therefore carry a potential to support existential resilience. Existential resilience, in this context, is integrated with existential aspects of health and sustainability The course is interdisciplinary and research-based, combining perspectives from the humanities with findings from research in medicine and the health sciences. It combines perspectives from art history and aesthetic theory, medical humanities and sustainability studies. It covers topics like aesthetic empathy, presence, meaningmaking, and imagination, and how existential resilience link the individual, communal, and planetary levels of human life. The course also discusses different sources of knowledge about arts and aesthetics in relation to existential resilience, including empirical observation, philosophical approaches, introspection, and embodied experience. It covers also how creative and aesthetic experiences can be facilitated and mediated in varying contexts.